Nathalie Demme, M.Sc.

| Address: | Computer Vision Group |
| Department of Mathematics and Computer Science | |
| Friedrich Schiller University of Jena | |
| Inselplatz 5 | |
| 07743 Jena | |
| Germany | |
| Phone: | +49 (0) 3641 9 46335 |
| E-mail: | nathalie (dot) demme (at) uni-jena (dot) de |
| Room: | 3018 |
| Links: |
Curriculum Vitae
| since 2025 | Research Associate / PhD Student | |
| Computer Vision Group, Friedrich Schiller University Jena | ||
| Topic: “Medical Image Segmentation and Classification using | ||
| Deep Federated Learning” | ||
| 2023 – 2025 | M.Sc. Bioinformatics | |
| Friedrich Schiller University Jena | ||
| Master Thesis: “Automatic Sleep Phase Classification in | ||
| Preterm Infants using Machine Learning” | ||
| 2023 – 2025 | Research Assistant | |
| BioImaging Group, University Hospital Jena | ||
| Topic: “Design of Algorithms for Extracting Clinically Relevant | ||
| Information From Sleep Data” | ||
| 2017 – 2022 | B.Sc. Bioinformatics | |
| Friedrich Schiller University Jena | ||
| Bachelor Thesis: “Evolutionary Conservation of LncRNAs H19, | ||
| MEG3, TUG1 in Connection with T1DM” |
Research Interests
- Federated Learning
- Time Series Analysis
- Applied Machine Learning and Deep Learning
Publications
2025
Nathalie Demme, Maha Shadaydeh, Laura Schieder, Claus Doerfel, Stella Jähkel, Knut Holthoff, Hans Proquitté, Joachim Denzler, Jürgen Graf:
Towards unobtrusive sleep stage classification in preterm infants using machine learning.
Biomedical Signal Processing and Control. 108 : pp. 107904. 2025.
[bibtex] [web] [doi] [code] [abstract]
Towards unobtrusive sleep stage classification in preterm infants using machine learning.
Biomedical Signal Processing and Control. 108 : pp. 107904. 2025.
[bibtex] [web] [doi] [code] [abstract]
In the neonatal intensive care unit (NICU), preterm infants are usually unable to fulfil their sleep demands due to frequent disruptions. Real-time sleep monitoring could be an essential tool not only to shift elective care to their wake periods but also to track their developmental sleep profile as an indicator of healthy brain maturation. The current gold standard for sleep measurement, polysomnography, is invasive and labour-intensive, limiting its applicability for continuous monitoring. We propose an automatic sleep stage classification method using only the routinely available electrocardiogram (ECG) and patient movement data recorded with a piezo mat. For this study we recorded data from 28 preterm infants (13 females and 15 males) at 35.7 \pm 0.5 weeks postmentrual age. We employed a support vector machine (SVM) to classify sleep stages into wakefulness (W), active sleep (AS), and quiet sleep (QS). The combined piezo + ECG model demonstrated superior accuracy (92 \%) and strong agreement with expert annotations (Cohen's kappa = 0.83) compared to ECG-only or piezo-only models. This approach offers a reliable, unobtrusive solution for continuous sleep monitoring in NICUs, facilitating individualised, sleep-based medical care for preterm infants.
